2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]- - Names and Identifiers
Name | N-T-boc-D-3-(2-naphthyl)alanine
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Synonyms | Boc-D-2-Nal-OH Boc-3-(2-Naphthyl)-D-alanine Boc-D-3-(2-Naphthyl)-alanine N-T-boc-D-3-(2-naphthyl)alanine NALPHA-tert-Butoxycarbonyl-3-(2-naphthyl)-D-alanine 2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-
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CAS | 56583-58-5 76985-10-9
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InChI | InChI=1/C18H21NO4/c1-18(2,3)23-17(22)19-15(16(20)21)11-12-8-9-13-6-4-5-7-14(13)10-12/h4-10,15H,11H2,1-3H3,(H,19,22)(H,20,21)/p-1/t15-/m1/s1 |
2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]- - Physico-chemical Properties
Molecular Formula | C18H21NO4
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Molar Mass | 315.36 |
Melting Point | 90℃ |
Boling Point | 512.2°C at 760 mmHg |
Flash Point | 263.6°C |
Vapor Presure | 2.58E-11mmHg at 25°C |
Storage Condition | −20°C |
MDL | MFCD00076900 |
2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]- - Risk and Safety
2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]- - Introduction
N-T-boc-D-3-(2-napthyl) alanine is an organic compound containing phenylalanine and naphthyl functional groups in its chemical structure. It usually exists in solid form and its chemical formula is C25H25NO4.
N-T-boc-D-3-(2-napthyl) alanine a protecting group strategy commonly used in peptide synthesis. A protecting group is a chemical group added during the synthesis process to protect certain functional groups in the reaction and prevent unnecessary reactions. Boc (tert-butoxycarbonyl) is a commonly used protecting group that can be removed under specific conditions. Thus, N-T-boc-D-3-(2-napthyl) alanine can be used as a protected amino acid in peptide synthesis.
the method for preparing N-T-boc-D-3-(2-naphthyl)alanine is relatively complicated, and generally requires the synthesis of multiple intermediates, including naphthyl-substituted phenylacetone, which is then reacted with Boc-amino alcohol to obtain Boc-D-β-naphthylphenylacetone, and finally N-T-boc-D-3-(2-naphthyl)alanine is prepared by condensation reaction with aminopropionic acid.
Regarding safety information, N-T-boc-D-3-(2-napthyl) alanine has a certain degree of stability under normal conditions. However, it may be irritating to the skin, eyes and respiratory tract, so protective equipment should be worn during operation. In addition, as a chemical substance, it should be stored in a dry, well-ventilated place, away from fire and oxidants. Refer to the relevant safety data sheets for specific safe operation and handling. When using or handling N-T-boc-D-3-(2-napthyl) alanine, it is recommended to follow the laboratory's safety guidelines and take appropriate safety measures.
Last Update:2024-04-10 22:29:15